Summary of Modern Study on Qiju Dihuang (Eye Sight Formula^™⁾ Capsule

Chinese Use: Central retinitis, glaucoma, senile cataract, neuropapillitis, cerebral concussion sequelae, hypertension, chronic hepatitis.

Modern studies on Pharmacodynamical reveal that this product yields actions of strengthening the immunity and anti-senility.

1. Promotion of immunity: 200% Decoction of this product is administered to young mice by gastric perfusion in a dose 60g/kg daily for 2 consecutive weeks. The positive percentage of acidic ANAE lymphocytes in peripheral blood and the number PFC of the spleen are all markedly higher than that in the control group, demonstrating that this product yields an effect of strengthening the function of T, B- lymphocyte. By adopting the receptor tests of EA rosette (Fc receptor) and YC rosette (C_3breceptor) exams, it is demonstrated that this product also markedly strengthens the function of abdominal macrophage C_3breceptor in young mice, but yields little effect on the Fc receptor, demonstrating that this product possesses multifacet function for strengthening the immunity; its mechanism of action may be optional.

2. Anti-senility: 200% Decoction of this product is given by gastric perfusion to senile mice in a dose 60g/kg daily for 2 successive weeks. The peripheral blood positive ANAE lymphocyte percentage is markedly elevated, and even exceeding that of the young control group. It also markedly promotes the PFC, and markedly recovers the senilized immunity in senile mice, demonstrating that this product yields certain anti-senilily action.

Clinically, this product was applied in central retinitis, glaucoma, papillitis, sequelae of cerebral concussion, hypertension, and chronic hepatitis.

1. Eye diseases: Modification of this product was applied to treat 140 cases of old retinitis for 9 weeks, 22 cases were cured; 21 cases, markedly effective; 70 cases, ameliorated; the total effective rate being 80.27%. When this product was used with Rhizoma Dioscorea excluded and Radix Angelica sinensis, Radix Salviae miltiorrhigae, Lignum Sappan added for a case of central retinitis of the type of yin deficiency of liver-kidney, with asthenic fire flaring upward for 3 months. The eyesight was totally recovered from 0.2 and 0.8 before treatment to 0.9 and 1.5 after the treatment. A case of glaucoma was treated with modification of this product for over 1 months, the eyesight was also recovered completely. Another case of sudden blindness due to fundal bleeding was treated with over 20 doses of this decoction, the bleeding was absorbed and vision recovered. 21 cases (32 eyes) of degeneration of macula lutea were treated with oral solution of this product, with another 19 cases (32 eyes) administrated with Vit. E (0.1g, t.i.d.) as control for 4 months. Results showed that the symptoms vanished in 14 eyes (43.8%) in the treatment group; that of the control group, 5 eyes (15.6%). Amster test in the treatment group revealed that 12 eyes out of the 18 abnormal eyes recovered to normal, while only 5 out of the 16 abnormal eyes in the control group recovered. For eyesight, 20 eyes in the treatment group recovered. (Increase of 2 lines as compared with the original vision), representing 62.5%, vision in 5 eyes (15.6%) was aggravated. While in the control group, the results being 4 eyes (12.5%) and 12 eyes (37.5%) respectively.

2. Sequelae of cerebral contusion: 12 cases were treated with modification of this product for an average of 12.5 doses. 9 cases were cured for short-term, 1 case ameliorated, the total effective rate being 83.3%.

3. Chronic viral hepatitis: 32 cases were treated (18 were active cases, 14 delayed chronic cases, all liver protection agents were interrupted), one pill, b.i.d. for the 10 cases in the control group were administered granules one package, t.i.d. and 3 tablets t.i.d. for 3 months as a course. After 1~2 course of treatment, 23 cases in the treatment group had symptoms basically vanished; 7 cases, ameliorated; 2 cases remained unchanged; the total effective rate being 93.8%. 12 cases had the size of liver shrunk to normal. 2 cases had spleen size returned to normal. The results in the control group revealed that 1 case had symptoms basically disappeared, 5 cases ameliorated, 4 cases unchanged, the total effective rate being 60%. 1 case had liver size turned to normal. The long-term effect of this product is also superior to the control group.

4. Hypertension: 16 cases of primary hypertension of deficient kidney yin type (I stage) were treated with this product for 8~12 weeks. The clinical symptoms were markedly ameliorated, with marked lowering of the score for 7 symptoms.

Excerpt from A Guide to TCM Products, China Academy of Traditional Chinese Medicine, 2003

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any diseases.