Summary of Modern Studies on Duzhong Yutai (Healthy Pregnancy™) Capsule

 

Chinese Use: Habitual miscarriage, habitual abortion,threatened abortion.

 

Modern studies on pharmacodynamics reveal that this product yields actions of promoting secretion of ovarian hormone, promoting ovulation, and promoting the growth of ovary and uterus.

 

1.              Promoting secretion of ovarian hormone: Female rabbits are randomly assigned to experimental group and control group. The former group is given 27.5g/kg of this product, once daily. For the control group, no medication is given. Other treatments are the same as the experimental group for 26 days. The animals are killed by air emboli on the 13^th, 20^th, 26^th days after medication. Internal sexual organs such as uterus and ovary are taken out for observation of changes under naked eyes and microscope. It can be seen that: (1) Mild hyperplasic of endometrium, with increased glands, marked secretion, which is increased with the increase of medication days.(secretion is transition from early to late stages ).For the control group , there are less glands ,with proliferation: A few rabbits reveal secretion, but less conspicuous than the test group. Thus, it can be inferred that this product may promote the secretion of luteotrophic hormone, or promote the secretion function of female sex hormone. (2) The ovary of rabbit in the medication group has more corpus lutcum. Those rabbits receive medication over 21 days have luteum cells distributed over the whole ovary. That in the control group, only in certain part of the ovary without corpus hemorrhagicum. The formation and its existence are related to the female sex hormone and pituitary luteotrophic hormone. Thus, it is inferred that this product can promote the level of female sex hormone, or even excite the hypothalamus-pituitary function.(3)The rabbits in medication group during observation reveal overlapping sexual behavior, but absent in the control group. This overlapping activity is an indication of oestrous period, based on the stimulation of estrogen produced in the ovary, indicating that this product stimulates the ovary to secret estrogen.

2.              Promotion of ovulation: oral medication of this product is given (dosage 27.5g/kg) for over 21 days. In some individual animals, corpus albicans and corpus hemorrhagicum can be seen which is an indirect indication of ovulation.

3.              Promoting the formation and growth of ovary and uterus: Female rabbit fed with this product (27.5g/kg) for 26 days are examined for its ovary and uterus under the microscope. It can be seen that the rabbits in medication group have richer blood supply to the ovary and uterus than the control group. Since the ovarian blood supply does affect its secretion, therefore, it can be concluded that this product can promote blood circulation through which the metabolism of the ovary and uterus is raised, and as a result their growth are promoted.

 

Clinically, this product was applied in habitual abortion and threatened abortion.

1.      Prevention and treatment of habitual and threatened abortion: Medication of this product (5g, tid, with 3 months as a therapeutic course, for 1~3 courses, same below), 124 cases were treated, the total effective rate being 94.35%.

2.      Sterility: 10 male cases were treated. Among them, 3 cases were impotence, 1 case of non-ejaculation, 6 cases of abnormal seminal fluid. 7 female cases, among them, 2 cases of underdeveloped uterus, 5 cases were dysfunction of corpus luteum and anovulation .1~3 courses of this product were given (3 months as a course), all cases were cured and fertilized.

 

Excerpt from A Guide to TCM Products, China Academy of Traditional Chinese Medicine, 2003

 

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any diseases.